داستان آبیدیک

proto spacer


فارسی

1 زیست شناسی:: پروتو اسپیسر

Even though CRISPR can provide high levels of phage resistance, a relatively small propor¬tion of viruses retain the ability to infect the "immunized" host. These viral particles have specifically mutated the proto-spacer (sequence within the invading nucleic acid that matches a CRISPR spacer), with a single point mutation that allows the viruses to overcome immunity, which indicates that the selective pressure im-posed by CRISPR can rapidly drive mutation patterns in viruses (17, 18, 23).

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